A synthesized peptide derived from human AKR1C3, corresponding to a region within C-terminal amino acids.
A synthesized peptide derived from human AKR1C4, corresponding to a region within N-terminal amino acids.
A synthesized peptide derived from human AKR1CL2, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human AKR1D1.
The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.
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