CNCKAPETALCARRCQQH-NH2(Disulfidebridge:C1-C11,C3-C15)
C79H131N31O24S4
A synthesized peptide derived from human APBA1, corresponding to a region within N-terminal amino acids.
A synthesized peptide derived from human APBA2, corresponding to a region within the internal amino acids.
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.
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