Carcinoembryonic antigen M2A (D2-40) is a 40kDa O-linked sialoglycoprotein that is a selective marker of lymphatic endothelium in normal tissues and vascular lesions. D2-40 was expressed on the surface of spermatogenic cells, germ cell tumors, lymphatic endothelial cells and mesothelial cells in the testis, and on the surface of mesothelial cells and primordial germ cells. Studies have shown that D2-40 is stained in the lymphatic endothelium, but not in the adjacent capillaries. It is usually used to mark the lymphatic endothelium in tissues, which is helpful for the diagnosis of lymphatic endothelial cell tumors and the judgment of lymphatic invasion and metastasis in other tumor tissues.
Desmin, one of the intermediate fibroins, it is expressed in smooth muscle cells, cardiomyocytes, skeletal muscle cells, myoepithelial cells and their tumors. It is mainly used in the judging and differential judging of uterus, skin, gastrointestinal tract and other rhabdomyosarcomas and myoepitheliomas. High temperature repair can enhance the staining color.
Lascia la tua email e seleziona le aree che vuoi seguire per ricevere novita di prodotto, approfondimenti tecnici e promozioni piu pertinenti.
Puoi scegliere le macro-aree Life Science e Diagnostica oppure le singole specializzazioni.
Seleziona uno o piu ambiti di interesse per ricevere comunicazioni piu utili e mirate.
Aggiornamenti su ricerca, strumentazione e applicazioni per il mondo Life Science.
Novita, approfondimenti e promozioni per laboratori diagnostici e flussi operativi.
2025 TEMA Ricerca - All Rights Reserved.