Mast cell tryptase(MCT) is widely expressed in respiratory tract, gastrointestinal tract, skin and other tissues. It is mainly used in the study of respiratory system, gastrointestinal system diseases and their tumors.
MDM2 is a ubiquitin ligase located on the long arm of chromosome 12. Amplification of the long arm of chromosome 12 is prevalent in well-differentiated liposarcoma and dedifferentiated liposarcoma, resulting in the overexpression of the products of several oncogenes in this region, including MDM2 and CDK4. Therefore, combined detection of MDM2 and CDK4 can be used to distinguish well-differentiated liposarcoma from spindle cell/pleomorphic lipoma or classic lipoma, and also to distinguish dedifferentiated liposarcoma from other high-grade sarcomas.
Melan A is a transmembrane protein composed of 118 aa, which is expressed in skin, retina and most melanocytes as well as melanoma and angiomyolipoma. MART-1/melan A Monoclonal Aantibody is helpful for the classification of melanoma and adrenocortical carcinoma, as well as the classification of angiomyolipoma.
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