Nestin is a 200kDa class Ⅵ intermediate filament protein that is mainly expressed in early embryonic neuroepithelial stem cells and during tendon and neuromuscular joint development. "Nestin is not specific for the central nervous system because it identifies not only the most primitive neuroepithelium but also other embryonic tissues." Nestin is expressed in almost all glioblastomas and melanomas (primary and metastatic), but it is not expressed in any metastatic carcinoma.
Neuron nucleus (NeuN) is a neuronal protein, which is expressed in most post-mitotic neurons of the central nervous system and peripheral nervous system, but not in retinal cells, Cajal-Retzius cells, Purkinje cells, sympathetic ganglion cells, etc. NeuN is of great value in the identification of neuron-derived tumors, and is mainly used for the diagnosis and differential diagnosis of glioneuronal tumors and neurocytomas.
Lascia la tua email e seleziona le aree che vuoi seguire per ricevere novita di prodotto, approfondimenti tecnici e promozioni piu pertinenti.
Puoi scegliere le macro-aree Life Science e Diagnostica oppure le singole specializzazioni.
Seleziona uno o piu ambiti di interesse per ricevere comunicazioni piu utili e mirate.
Aggiornamenti su ricerca, strumentazione e applicazioni per il mondo Life Science.
Novita, approfondimenti e promozioni per laboratori diagnostici e flussi operativi.
2025 TEMA Ricerca - All Rights Reserved.