This gene encodes a nucleolar transcriptional regulator that was first identified by its ability to bind specifically to the Myb proto-oncogene protein. The encoded protein is thought to play a role in many cellular processes including response to nucleolar stress, tumor suppression and synthesis of ribosomal DNA. Alternate splicing results in multiple transcript variants.
A synthesized peptide derived from human MYBPC1, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human MYBPC2, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human MYBPC3, corresponding to a region within C-terminal amino acids.
A synthesized peptide derived from mouse MYCB, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human MYCBP2, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human MYCBP, corresponding to a region within N-terminal amino acids.
A synthesized peptide derived from human MYCL.
A synthesized peptide derived from human MYCNOS, corresponding to a region within C-terminal amino acids.
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas.
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