MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy.
A synthesized peptide derived from human MYL4, corresponding to a region within N-terminal amino acids.
A synthesized peptide derived from human MYL6, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human MYL6B, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human MYL7, corresponding to a region within the internal amino acids.
Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene.
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