Neurogenin-1is aproteinthat in humans is encoded by theNEUROG1gene. Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis. NEUROG1 has been shown to interact with CREB-binding protein and decapentaplegic homolog 1.
A synthesized peptide derived from human NEUROG2, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human NEUROG3, corresponding to a region within N-terminal amino acids.
The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).
A synthesized peptide derived from human Neurogranin, corresponding to a region within N-terminal amino acids.
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