A synthesized peptide derived from human PCGF1.
A synthesized peptide derived from Human PCGF3.
A synthesized peptide derived from human PCK1, corresponding to a region within C-terminal amino acids.
This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene,along with GTP,catalyzes the formation of phosphoenolpyruvate from oxaloacetate,with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin,glucocorticoids,glucagon,cAMP,and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
A synthesized peptide derived from human PCK2, corresponding to a region within the internal amino acids.
This gene encodes a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of guanosine triphosphate (GTP). A cytosolic form of this protein is encoded by a different gene and is the key enzyme of gluconeogenesis in the liver. Alternatively spliced transcript variants have been described.
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