A synthesized peptide derived from human ARMX3, corresponding to a region within N-terminal amino acids.
A synthesized peptide derived from human ARNT, corresponding to a region within N-terminal amino acids.
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities.
A synthesized peptide derived from human ARP-1, corresponding to a region within N-terminal amino acids.
A synthesized peptide derived from human ARP2, corresponding to a region within N-terminal amino acids.
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