This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.
A synthesized peptide derived from human VPRBP, corresponding to a region within N-terminal amino acids.
A synthesized peptide derived from human VPREB1, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human VPREB3.
A synthesized peptide derived from human VPS11, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human VPS13A.
A synthesized peptide derived from human VPS13B.
A synthesized peptide derived from human VPS16, corresponding to a region within the internal amino acids.
Inserisci la tua e-mail e seleziona le aree di interesse per ricevere le ultime novità, approfondimenti e promozioni.
Seleziona uno o più ambiti di interesse per ricevere comunicazioni più utili e mirate.
2025 TEMA Ricerca - All Rights Reserved.
