This gene encodes a member of the WIPI or SVP1 family of WD40 repeat-containing proteins. The protein contains seven WD40 repeats that are thought to fold into a beta-propeller structure that mediates protein-protein interactions, and a conserved motif for interaction with phospholipids. The human genome contains several pseudogenes of this gene.
A synthesized peptide derived from human WDR46, corresponding to a region within the internal amino acids.
A synthesized peptide derived from Human WDR48.
A synthesized peptide derived from human WDR5, corresponding to a region within N-terminal amino acids.
A synthesized peptide derived from Human WDR60.
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. The encoded protein interacts with serine/threonine kinase 11, and is implicated in cell growth arrest.
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