A synthesized peptide derived from human APOE, corresponding to a region within the internal amino acids.
Apolipoprotein E (Apo-E),is a member of the apolipoprotein A1/A4/E family. ApoE is a major protein component of serum LDL,VLDL,HDL,and chylomicrons. APOE may function in mediating the binding,internalization,and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. APOE is usually secreted in plasma. Phosphorylation sites are present in the extracellular medium.
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