A synthesized peptide derived from human APP, corresponding to a region within C-terminal amino acids.
A synthesized peptide derived from human APPBP1, corresponding to a region within N-terminal amino acids.
A synthesized peptide derived from human APPBP2, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human APPL1, corresponding to a region within the internal amino acids.
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
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