The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein.
A synthesized peptide derived from human ARPP19, corresponding to a region within N-terminal amino acids.
A synthesized peptide derived from human ARPP21, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human ARRB1, corresponding to a region within C-terminal amino acids.
A synthesized peptide derived from human ARRB1.
A synthesized peptide derived from human ARRB1, corresponding to a region within the internal amino acids.
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