PA2G4 (EBP1),first identified as an ErbB3 binding protein,is a 38 kDa protein that is widely expressed in cultured cells and tissues. The presence of several functional domains such as a nuclear localization sequence (NLS),LxxLL and LxCxE suggests the involvement of Ebp1 in cell signaling pathways and gene transcription regulation. This antibody is a mouse mono-clonal antibody raised against full length PA2G4 of human origin.
A synthesized peptide derived from human PAAF1.
A synthesized peptide derived from human PABP1, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human PABP2, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human PABP2, corresponding to a region within C-terminal amino acids.
A synthesized peptide derived from human PABPC1L2A; PABPC1L2B.
This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.
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