This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.
A synthesized peptide derived from human PABPC3, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human PABPC4, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human PABPC5, corresponding to a region within the internal amino acids.
affinity purified
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