The protein encoded by this gene is a phosphoprotein that may upregulate the PDGFA-stimulated growth of fibroblasts and also downregulate the mitogenicity of PDGFB. The encoded protein in rodents has been shown to bind PDGFA with a low affinity.
A synthesized peptide derived from human PDCD1LG2, corresponding to a region within the internal amino acids.
Programmed cell death 1 ligand 2(also known as PD-L2, B7-DC) is aproteinthat in humans is encoded by thePDCD1LG2gene.PDCD1LG2 has also been designated asCD273(cluster of differentiation273). Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
A synthetic peptide from human PDCD1LG2
A synthesized peptide derived from human PDCD2, corresponding to a region within N-terminal amino acids.
A synthesized peptide derived from human PDCD2L, corresponding to a region within the internal amino acids.
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