A synthesized peptide derived from human ARL11, corresponding to a region within the internal amino acids.
This gene encodes a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancers.
A synthesized peptide derived from human ARL13B, corresponding to a region within N-terminal amino acids.
A synthesized peptide derived from human ARL14.
A synthesized peptide derived from human ARL15, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human ARL1.
The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner. Alternative splicing results in multiple transcript variants encoding different isoforms.
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