This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known.BRD3 (Bromodomain Containing 3) is a Protein Coding gene. Diseases associated with BRD3 include Foodborne Botulism and Infant Botulism. GO annotations related to this gene include chromatin binding and lysine-acetylated histone binding. An important paralog of this gene is BRD2.
A synthesized peptide derived from human Brd4, corresponding to a region within N-terminal amino acids.
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif whicHuman, Mouseay be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
A synthetic peptide from human Brd4
A synthesized peptide derived from human BRD7, corresponding to a region within the internal amino acids.
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