A synthesized peptide derived from human NCOA6, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human NCOA7, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human NCoR1, corresponding to a region within N-terminal amino acids.
Purified recombinant fragment of human NCOR1 expressed in E. Coli.
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.
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