This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants.
A synthesized peptide derived from human OXA1L, corresponding to a region within C-terminal amino acids.
OXA1L (OXA1L Mitochondrial Inner Membrane Protein) is a Protein Coding gene. The OXA1L gene,located on 14q11.2,is conserved in chimpanzee,Rhesus monkey,dog,and cow,etc. This gene encodes an evolutionarily conserved protein that is localized to the inner mitochondrial membrane. The encoded protein is essential for the translocation of the N-terminal tail of subunit 2 of cytochrome c oxidase and is involved in the assembly of the cytochrome c oxidase and ATPase complexes of the mitochondrial respiratory chain. In humans,the mitochondrial inner membrane protein Oxa1L is involved in the biogenesis of membrane proteins and facilitates the insertion of both mitochondrial- and nuclear-encoded proteins from the mitochondrial matrix into the inner membrane. The C-terminal approximately 100-amino acid tail of Oxa1L (Oxa1L-CTT) binds to mitochondrial ribosomes and plays a role in the co-translational insertion of mitochondria-synthesized proteins into the inner membrane.
A synthesized peptide derived from human OXCT1, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human OXER1, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human Oxr1, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human OXT, corresponding to a region within the internal amino acids.
The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition.
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