This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons.
A synthesized peptide derived from human NGFR, corresponding to a region within the internal amino acids.
A synthetic peptide from human NGF
A synthetic peptide from human NGFR
A synthesized peptide derived from human NGRN, corresponding to a region within N-terminal amino acids.
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